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Lior Sapir is a Fellow at the Manhattan Institute for Policy and Research, where he specializes in gender medicine policy. His research focuses on the scientific evidence underlying pediatric gender-affirming care and the policy frameworks governing medical interventions for minors.
Sapir has gained recognition for breaking stories about major medical organizations that have begun to question the evidence base for pediatric gender interventions. His work examines how recommendations for gender-affirming care have evolved and how they compare to the underlying scientific literature.
On the Kim Monson Show in April 2025, Sapir discussed the growing international movement away from pediatric gender interventions, citing the United Kingdom's landmark Cass Review as a turning point. He explained how gender-affirming care recommendations had outpaced the available scientific evidence and detailed the shifting positions of medical institutions both domestically and internationally.